Latest updates
Australian biotech giant CSL to start vaccine manufacture on Monday
By Mathew Dunckley
Australian biotech giant CSL will begin making a COVID-19 at its facility in north west Melbourne on Monday.
CSL on Sunday announced it would start manufacturing the University of Oxford/AstraZeneca AZD1222 COVID-19 vaccine candidate at its plant in Broadmeadows.
Australian biotech giant CSL will begin making a COVID-19 at its facility in north west Melbourne on Monday.Credit:AP
In a statement the company said it had separate contracts with AstraZeneca and the Australian government to make about 30 million doses of the AZD1222 vaccine candidate with the aim of having the first doses available in the "first half of 2021, pending the outcome of clinical trials and regulatory approval".
Here's some more of the statement:
"The manufacturing process will start with the thaw of vials containing vaccine cells. The cells - frozen under liquid nitrogen to preserve their integrity - need to be thawed in preparation for replication in the bioreactors at the company’s Broadmeadows facility. After growing in the bioreactors, the vaccine is then filtered and purified leaving just the antigen, or vaccine product. It is then ready for final formulation and filling into dosage vials.
"The vial thaw milestone follows several months of close collaboration and preparation by CSL and AstraZeneca technical experts. During 2020/2021, CSL will manufacture eight large scale batches of vaccine drug substance. Should the vaccine demonstrate its safety and efficacy in clinical trials that are currently underway, it is anticipated that it will require a two dose per person regime.
"The vaccine will not be released for use until the relevant clinical trial and manufacturing data are reviewed and approved by the Australian government regulatory authority; the Therapeutic Goods Administration (TGA)."
CSL is also manufacturing the University of Queensland's UQ-CSL V451 COVID-19 vaccine candidate.
"Multiple doses of the UQ-CSL V451 vaccine candidate have already been manufactured at the Broadmeadows facility and are held in readiness to progress the vaccine to Phase 2b/3 clinical trials. The decision to proceed to the next clinical trial stage will be made once Phase 1 data has been released and analysed," the company
CSL chief scientific officer Andrew Nash.
“This is an important milestone and marks the end of many months of around the clock preparation by our skilled personnel globally within CSL Behring, Seqirus and research and development. Both campaigns are still technically challenging but at this time we are tracking well and expect to produce the AZD1222 and the UQ-CSL V451 vaccine for Australia by mid-2021.
"There’s still a long way to go and our first priority resolutely remains the safety and efficacy of the vaccines we produce. We are undertaking these manufacturing activities at-risk and in parallel with the clinical trials and approvals processes in recognition of the significant urgency of the COVID-19 pandemic.”
Victoria records no new cases and no deaths for ninth day in a row
For the ninth day in a row, Victoria has recorded no new coronavirus cases and no deaths.
The 14-day rolling average has fallen to 0.4 and there are two cases with an unknown source between October 23 and November 5.
Biden expected to take steps to establish a new coronavirus taskforce
Democratic Party nominee Joe Biden has reached that magic milestone, winning at least 290 votes in the US Electoral College.
But while the gruelling election process might be over, the hard work for the president-elect lies ahead, not least the challenge of healing a sharply polarised nation, writes Damien Nowicki.
One of Biden’s key ambitions is to tackle the surge of new COVID-19 cases across the US, which have hit record highs in recent days.
The president-elect has said he will “listen to the scientists”, including Dr Anthony Fauci, who has been sidelined by President Donald Trump, and it is expected he will take steps to establish a new coronavirus taskforce.
Read more about what comes next now that Biden has won the presidency.
And for all updates about the US election, follow our live blog here.
COVID-19 the catalyst for sea change, as Sunshine Coast sees influx from Sydney and Melbourne
By Caitlin Fitzsimmons
Sydneysiders and Melburnians are moving to the Sunshine Coast in droves as COVID-19 proves a catalyst for a sea change, with families prepared to spend two weeks in quarantine and buy or rent houses sight unseen.
The warm weather, the relaxed lifestyle and relatively affordable housing in the coastal region north of Brisbane are luring singles and families dealing with the stresses of lockdown in the southern states, with the widespread adoption of remote working removing one former barrier to a sea change.
Danielle Fumagalli and Bruno Martins moved to the Sunshine Coast from Sydney.Credit:Paul Harris
Last week the Australian Bureau of Statistics reported a big shift in people moving from the capital cities to the regions, including a net loss of 14,000 in Sydney and 10,000 in Melbourne in the first half of the year. The net figure is the difference between the people leaving a place and those moving there.
From January to June a net 8000 Sydneysiders moved to other parts of NSW, while a net 3000 Sydneysiders moved to regional Queensland.
Read the rest of this story here.
Good morning
Good morning, Simone Fox Koob here to run today's coronavirus blog.
It's going to be a big day for Victorians, with Premier Daniel Andrews expected to announce a further easing of restrictions off the back of eight straight days with no new cases and no deaths.
Daniel Andrews will on Sunday announce which restrictions will be loosened.Credit:Eddie Jim
The 25-kilometre travel limit and the metro-regional border are set to be removed on Sunday and hospitality venues are likely to be allowed to seat 40 people indoors and 70 outdoors.
Meanwhile, Australian infectious disease experts are calling for a national digital check-in system for restaurants and pubs before the country's internal borders reopen, arguing it could trim up to eight critical hours off the time spent by contact tracers racing to identify contacts of COVID-19 positive cases.
Most Viewed in National
https://news.google.com/__i/rss/rd/articles/CBMiqwFodHRwczovL3d3dy5zbWguY29tLmF1L25hdGlvbmFsL2Nvcm9uYXZpcnVzLWxpdmUtdXBkYXRlcy12aWN0b3JpYS1zZXQtdG8tYW5ub3VuY2UtZnVydGhlci1lYXNpbmctb2YtcmVzdHJpY3Rpb25zLWF1c3RyYWxpYS1zLWRlYXRoLXRvbGwtcmVtYWlucy1hdC05MDctMjAyMDExMDgtcDU2Y2hsLmh0bWzSAasBaHR0cHM6Ly9hbXAuc21oLmNvbS5hdS9uYXRpb25hbC9jb3JvbmF2aXJ1cy1saXZlLXVwZGF0ZXMtdmljdG9yaWEtc2V0LXRvLWFubm91bmNlLWZ1cnRoZXItZWFzaW5nLW9mLXJlc3RyaWN0aW9ucy1hdXN0cmFsaWEtcy1kZWF0aC10b2xsLXJlbWFpbnMtYXQtOTA3LTIwMjAxMTA4LXA1NmNobC5odG1s?oc=5
2020-11-07 21:07:00Z
CBMiqwFodHRwczovL3d3dy5zbWguY29tLmF1L25hdGlvbmFsL2Nvcm9uYXZpcnVzLWxpdmUtdXBkYXRlcy12aWN0b3JpYS1zZXQtdG8tYW5ub3VuY2UtZnVydGhlci1lYXNpbmctb2YtcmVzdHJpY3Rpb25zLWF1c3RyYWxpYS1zLWRlYXRoLXRvbGwtcmVtYWlucy1hdC05MDctMjAyMDExMDgtcDU2Y2hsLmh0bWzSAasBaHR0cHM6Ly9hbXAuc21oLmNvbS5hdS9uYXRpb25hbC9jb3JvbmF2aXJ1cy1saXZlLXVwZGF0ZXMtdmljdG9yaWEtc2V0LXRvLWFubm91bmNlLWZ1cnRoZXItZWFzaW5nLW9mLXJlc3RyaWN0aW9ucy1hdXN0cmFsaWEtcy1kZWF0aC10b2xsLXJlbWFpbnMtYXQtOTA3LTIwMjAxMTA4LXA1NmNobC5odG1s
Bagikan Berita Ini
0 Response to "Coronavirus LIVE updates: Victoria set to announce further easing of restrictions as state records another day of no new cases; Australia's death toll remains at 907 - The Sydney Morning Herald"
Post a Comment